Five hundred years after a snake demon named Xiao Bai and the human Xu Xuan fell in love, the lovers are overjoyed to reunite. Unfortunately, due to the interference of the monk Fahai, their chance at a second romance ultimately ends in disaster, with Xiao Bai sealed under Leifeng Pagoda and her loyal sister Xiao Qing cast into the chaotic Asura Realm.

Within the Asura Realm, humans and demons from all historical eras who have died with a consuming obsession are gathered together. Along with several races of monsters, they all fight for survival. Stripped of the spiritual powers she painstakingly cultivated, Xiao Qing has to rely on new weapons and technology if she wants to stay alive. Together with a mysterious masked man, she fights to find a way back to her own realm—and to her sister.