Tanis, a child genius, is the youngest son of two mad scientists. His family has spent their lives withdrawn from normal society living on an isolated island, where the couple conducts experiments on Tanis' siblings that result in them gaining abnormal abilities. However, this activity is put to a stop when they are caught and arrested.

Tanis is brought by government officials to a more populated island, alongside his four siblings: Snow, a dog-human hybrid; Ashise, a plant-human hybrid; Aisley, a spider-human hybrid; and Suishi, a mind-reader. Being the only one who has not been genetically modified, Tanis takes on the responsibility of adapting his siblings to society, all while trying to conceal their' distinctive characteristics.