Madoka Kaname and Sayaka Miki are regular middle school girls with regular lives, but all that changes when they encounter Kyuubey, a cat-like magical familiar, and Homura Akemi, the new transfer student.

Kyuubey offers them a proposition: he will grant any one of their wishes and in exchange, they will each become a magical girl, gaining enough power to fulfill their dreams. However, Homura Akemi, a magical girl herself, urges them not to accept the offer, stating that everything is not what it seems.

A story of hope, despair, and friendship, Mahou Shoujo Madoka★Magica deals with the difficulties of being a magical girl and the price one has to pay to make a dream come true.