Since ancient times, the world of Remnant has been under constant threat by the Grimm: creatures of nightmare obsessed with destroying both humans and the half-human Faunus. To protect themselves, the four kingdoms of the world established academies that train young people to become huntsmen: warriors tasked with destroying Grimm.

In the kingdom of Vale, the cheerful 15-year-old Ruby Rose has always dreamed of a life at the prestigious Beacon Academy. Sadly, being too young, she can only watch as her elder sister, Yang Xiao Long, sets off for the academy alone. But everything changes when Ruby fights off a group of armed robbers, and the news of her skillful exploit reaches Beacon's headmaster, Professor Ozpin.

Ruby is over the moon when she receives an invitation to join the academy alongside her sister. Meanwhile, halfway across the world in the kingdom of Atlas, corporate heiress Weiss Schnee defies her father's wish and sets off for Beacon, her heart brimming with anxious resolve. At the same time, lonesome rogue Blake Belladonna abandons her vigilante group in hopes of finding a better life at the academy. When their paths converge, the meeting between the four girls is anything but friendly. With vastly different personalities and beliefs, they often end up clashing. However, when they work together, team RWBY begins to create ripples across Beacon, the likes of which have never been seen before.