College student Nao Kanzaki has always adhered to her name's meaning: "foolishly honest." However, after opening an unsolicited package containing one hundred million yen, she inadvertently accepts an invitation for the "Liar Game." In this tournament, contestants are encouraged to betray and deceive their opponents to gain a massive amount of cash; conversely, losing will incur a lifetime debt. With all hopes lost, her only option left is to seek help from a con artist.

On that same day, the infamous swindler Shinichi Akiyama is finally released from jail. This former psychology student is known for single-handedly bankrupting an entire company, and Nao believes he is her only chance at escaping her dire situation. At first, Shinichi is hesitant to commit another crime, ignoring Nao and her request. But after seeing her desperation and persistence, he agrees to assist her.

In this fraudulent world, Nao and Shinichi have their own motives. Yet, soon they see the true nature of not only the game but also everyone involved.

Liar Game was published in Dutch by Kana; in French by Tonkam; in German by Egmont Manga; in Spanish by Planeta DeAgostini; and in Turkish by Marmara Çizgi. The series was adapted into a two-season Japanese television series, with the first season airing in 2007 and the second season from 2009 to 2010. It also received two live-action films: Liar Game: The Final Stage in 2010 and Liar Game: Reborn in 2012. It was also adapted into a Korean live-action drama that aired from October 20, 2014, to November 25, 2014.