It's Shouko Komi's first day at the prestigious Itan Private High School, and she has already risen to the status of the school's Madonna. With long black hair and a tall, graceful appearance, she captures the attention of anyone who comes across her. There's just one problem though—despite her popularity, Shouko is terrible at communicating with others.

Hitohito Tadano is your average high school boy. With his life motto of "read the situation and make sure to stay away from trouble," he quickly finds that sitting next to Shouko has made him the enemy of everyone in his class! One day, knocked out by accident, Hitohito later wakes up to the sound of Shouko's "meow." He lies that he heard nothing, causing Shouko to run away. But before she can escape, Hitohito surmises that Shouko is not able to talk to others easily—in fact, she has never been able to make a single friend. Hitohito resolves to help Shouko with her goal of making one hundred friends so that she can overcome her communication disorder.

Komi-san wa, Comyushou desu. ranked eighth in the Best Print Manga category at the third Tsugi ni Kuru Manga Awards in 2017. It won the 67th Shogakukan Manga Award in the Shounen category in 2021.

The series was published in English as Komi Can't Communicate by VIZ Media under the Shonen Sunday imprint from June 19, 2019, to March 10, 2026. The series was simulpub digitally through VIZ Manga. It has also been published in German by Tokyopop since July 1, 2020; in Italian by J-POP since September 30, 2020; and in Brazilian Portuguese by Panini Comics since February 25, 2022.

The manga was adapted into a Japanese live-action TV series that aired from September 6, 2021, to November 1, 2021.