In a future one hundred million years away, after history has ended, myths have returned to life and giants stride across the land. Also wandering this world are Delos the wrestler and his odd partner Prome. Their mission brings them deep into an inhospitable desert where they make contact with the Scarabaei, a race of scarab people.

However, the Scarabaei have long suffered at the hands of a human empire encroaching on their lands, an empire they assume the very human Delos and his companion are part of. Forcing Delos to stand for the Empire's crimes, he is thrust into an arena with the Scarabaei's champion fighter Ogun. With his life on the line, Delos must not only confront this formidable warrior, but also the feelings of a whole tribe. Justice, pride, and survival hang in the balance.

Kentaro Miura originally planned Giganto Makhia as a commemorative project for the 20th anniversary of the Young Animal magazine, although it was not published until a few years after the milestone. This is Miura's first original project in 24 years since he began Berserk.

The series was published in English as Giganto Maxia by Dark Horse Comics on February 3, 2016. It was also released in Brazilian Portuguese by Panini Comics in January 2015; in Polish by Japonica Polonica Fantastica on December 13, 2018; in Spanish by Panini Comics on July 24, 2019; and in Russian by Istari Comics on May 27, 2022.