In the isolated, desolate, decrepit village of Dunwich, Massachusetts, Wilbur Whateley is the hideous son of Lavinia Whateley, a deformed and unstable albino mother, and an unknown father. Strange events surround his birth and precocious development. Wilbur matures at an abnormal rate, reaching manhood within a decade. Locals shun him and his family, and animals fear and despise him due to an unnatural, inhuman odor emanating from his body. All the while, his grandfather, a sorcerer, indoctrinates him into certain dark rituals and the study of witchcraft.